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Cocaine Use Disorder and CBD

A meta-study published in Pharmacology Biochemistry and Behavior found that cannabidiol (CBD) may be effective at treating cocaine use disorder. The paper, by a research team based in Brazil, examined 14 animal-model studies published over the course of five years and found that CBD reduces the frequency of cocaine self-administration. CBD may also interrupt the reward pathways in the brain that fuel addictive behavior.

One of the major limitations of the meta-study is that the findings are based entirely on animal models because, as the authors note, no trials about CBD and cocaine use disorder that involve humans have been conducted at this time. That will hopefully change.

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