Federal Agencies Set Standard Dose of THC

A joint announcement issued by the National Institute on Drug Abuse; the National Heart, Lung, and Blood Institute; the National Institute of Mental Health; and the National Cancer Institute, effective as of May 7, 2021, has decreed that a “new requirement to measure and report results using a standard [tetrahydrocannabinol] unit in all applicable human subjects’ research.” That standard unit is now 5 mg of THC. While the standardization is far from complete, as THC produces different effects in subjects depending how a sample is administered, the sample’s constituents, the individual’s genetic makeup, and other factors, it will make it easier to compare studies that involve THC exposure.


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